منابع مشابه
Accelerating drug discovery.
Drug development, from initial discovery of a promising target to the final medication, is an expensive, lengthy and incremental process. The ultimate goal is to identify a molecule with the desired effect in the human body and to establish its quality, safety and efficacy for treating patients. The latter requirements ensure that the approved medication improves patients’ quality of life, not ...
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Despite the continuing advancements in the treatment of cancer and the introduction of new therapies, responses still vary from patient to patient. In many cases, this variation remains unexplained, making it difficult to predict who will respond. For instance, immunotherapies targeting cytotoxic T lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1), and the PD-1 li...
متن کاملUsing a private desktop grid system for accelerating drug discovery
Drug design is a challenging and computationally intensive task. Chemists are often faced with handling huge amounts of data as well as with working with huge amounts of computational resources. This paper shows that using the BOINC system as a private, dedicated desktop grid a community, like the EU CancerGrid chemist community, can easily set up its own high-end infrastructure based on availa...
متن کاملEthnobotany, Ethnopharmacology and Drug Discovery
This manuscript is a review of a number of ethnobotany and ethnopharmacology texts and papers in order to arrive at current understanding and scope of ethnobotany and ethnopharmacology. It includes either a brief definition of both fields and presenting some examples on them. Also it has a glimpse on the geographical coverage of research works throughout the world, important issue of prope...
متن کاملethnobotany, ethnopharmacology and drug discovery
this manuscript is a review of a number of ethnobotany and ethnopharmacology texts and papers in order to arrive at current understanding and scope of ethnobotany and ethnopharmacology. it includes either a brief definition of both fields and presenting some examples on them. also it has a glimpse on the geographical coverage of research works throughout the world, important issue of property r...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 1994
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt0794-736